Cisplatin hearing monitoring
WebCisplatin-Associated Ototoxicity: A Review for the Health Professional Cisplatin-Associated Ototoxicity: A Review for the Health Professional J Toxicol. doi: 10.1155/2016/1809394. Epub 2016 Dec 27. Authors Jessica Paken 1 , Cyril D Govender 1 , Mershen Pillay 1 , Vikash Sewram 2 Affiliations WebCisplatin-based chemotherapy may cause hearing loss. People who have been treated for testicular cancer with cisplatin-based chemotherapy often experience both hearing loss …
Cisplatin hearing monitoring
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WebMar 25, 2024 · The aim of this study is to evaluate the current state of ototoxicity monitoring for patients receiving cisplatin chemotherapy in an academic medical center with particular attention to how closely monitoring adheres to national ototoxicity guidelines. Methods: Patient and ototoxicity related variables were analyzed. WebCisplatin, an effective antineoplastic drug used in the treatment of many cancers, has ototoxic potential, thus placing cancer patients, receiving this treatment, at risk of …
WebJan 27, 2024 · In cohort 1 of the IMvigor210 study, atezolizumab was studied as a first-line treatment in this group of chemotherapy-naïve cisplatin-ineligible patients, defined as those with a glomerular filtration rate (GFR) > 30 but <60 mL/min, hearing impairment, grade 2 or higher peripheral neuropathy, or ECOG performance status of ≥2 . Atezolizumab ... Webmonitoring and prevention of ototoxicity by cisplatin. True estimates of ototoxicity from cisplatin are difficult to quantify given differing scales and classification systems used in clinical trials to measure this adverse event.3 Furthermore, scales that rely on subjective reporting of hearing loss likely underestimate the true
WebJun 21, 2024 · Hearing loss of grade 1 or higher occurred in 18 of 55 children (33%) in the cisplatin-sodium thiosulfate group, as compared with 29 of 46 (63%) in the cisplatin-alone group, indicating a 48% lower incidence of hearing loss in the cisplatin-sodium thiosulfate group (relative risk, 0.52; 95% confidence interval [CI], 0.33 to 0.81; P=0.002). WebStudy sample: Twenty-two male veterans treated with cisplatin for various cancers provided data from a total of 71 monitoring appointments. Data collection and analysis: Data were collected prospectively from one ear of each participant as designated below.
WebMay 19, 2016 · Dr. Chang's clinical practice is based at the Lucile Packard Children's Hospital, and is focused on Pediatric Otology. He has specific …
WebOct 20, 2024 · Cumulative dose of cisplatin is an important predictor of development of ototoxicity. Baseline and periodic audiometric monitoring could detect ototoxicity early which leads to possible... how to take aloe vera plantWebCisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head and neck cancers. Approximately 500,000 patients diagnosed annually with these cancer types in the United States could be candidates for treatment with cisplatin. There is a 5-fold increase in the … how to take albuterolWebMay 1, 2005 · Monitoring hearing in patients receiving ototoxic drugs provides audiologists opportunities to counsel patients and their families regarding ototoxicity-induced hearing … ready lane passport cardWebApr 13, 2024 · Cisplatin therapy is used in a variety of treatment protocols, but it is most commonly used in gynecological (ovarian and cervical) and head and neck cancers. In … how to take amcat testWebApr 17, 2024 · For patients treated with the chemotherapeutic drug cisplatin, one common consequence of treatment is permanent hearing loss. Reported rates of cisplatin … ready law firm houstonWebFeb 11, 2024 · Cisplatin is a highly effective chemotherapeutic drug used against a wide range of childhood and adult cancers, but cisplatin crosses into the cochlea, which often results in permanent sensorineural cisplatin-induced hearing loss (CIHL). how to take amazon fire tablet off safe modeWebOct 1, 2024 · Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report Authors how to take an ach payment