Cisplatin drugbank

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August undefined, 2024

WebNov 30, 2015 · Thiosulfuric acid is a sulfur donor used sequentially with sodium nitrite for the reversal of life-threatening acute cyanide poisoning. Also used to reduce the risk of ototoxicity associated with cisplatin. Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. WebCisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare cases of clinically apparent, acute liver injury.

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WebOct 30, 2015 · DrugBank Accession Number DB09293 Background. Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of … WebSep 18, 2024 · NCBI Bookshelf how big is an a3 sheet in cm

Regulation of copper transporter 2 expression by copper and cisplatin ...

WebDisease. Known drugs (DrugBank IDs). Top 10 ranked predictions.; HD (OMIM ID: 143100) Baclofen (DB00181) Olanzapine (DB00334), Quetiapine (DB01224), Ziprasidone ... WebMitoxantrone has been shown in vitro to inhibit B cell, T cell, and macrophage proliferation and impair antigen presentation, as well as the secretion of interferon gamma, TNFa, and IL-2. Mechanism of action. Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and ... WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research ... Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest. Invest New Drugs. 2011 Aug;29(4):627 ... how many nucleotides aau gcg aug

cis-Diamminedichloroplatinum induces peroxisomes as well as ... - DrugBank

WebCisplatin Prices, Coupons and Patient Assistance Programs. Cisplatin is a member of the alkylating agents drug class and is commonly used for Anal Cancer, Bladder Cancer, … WebThe present findings suggest that induction of P450 by cisplatin may take part in the renal injury or nephrotoxicity of cisplatin. DrugBank Data that Cites this Article Drug Enzymes. Drug Enzyme Kind Organism Pharmacological Action Actions; Cisplatin: Cytochrome P450 4A11: Protein: Humans: how many nuclear weapons in the ukWebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin. Biochem Pharmacol. 1998 Oct 15;56(8):1013-21. how big is an a2 sheet of paper

"WebFeb 16, 2024 · Warnings. Cisplatin can affect your nervous system, increase your risk of bleeding or infection, or harm your kidneys.. Call your doctor if you have a fever, mouth … " - Cisplatin drugbank

Cisplatin drugbank

Pentoxifylline: Uses, Interactions, Mechanism of Action - DrugBank

WebAbstract. Since response to platinum-based therapy in non-small-cell lung cancer (NSCLC) is poor, the present study was designed to rationally identify novel drug combinations in cell models including the A549 cell line and the cisplatin-resistant subline A549/Pt, characterized by reduced sensitivity to cisplatin-induced apoptosis and by upregulation … WebGeneric Name Digoxin DrugBank Accession Number DB00390 Background. Digoxin is one of the oldest cardiovascular medications used today. 5 It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. 7 Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. 25 This drug originates …

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WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... Regulation of copper transporter 2 expression by copper and cisplatin in human ovarian carcinoma cells. Mol Pharmacol. 2010 Jun;77(6):912-21. doi: 10.1124/mol.109.062836. Epub 2010 Mar 1. PubMed ID. WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (CBDCA, JM8), an analogue of cisplatin showing reduced toxicity in preclinical studies, was evaluated in 60 patients. Doses were given initially every 3 weeks and escalated from 20 to 520 mg/m2. Following …

WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. Structured drug data for data science & ML. ... Cisplatin (DB00515) Docetaxel (DB01248) Erlotinib (DB00530) Filgrastim (DB00099) Pegfilgrastim (DB00019) WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... we treated cisplatin damaged neuroblastoma cells with a pharmacological ROCK inhibitor (Y27632) or sham, and monitored cell survival, accumulation of a chemoresistant phenotype, and in vivo tumor …

Web846 rows · Generic Name. Sofosbuvir. DrugBank Accession Number. DB08934. …

WebL01XA — Platinum compounds. Drugs. Drug. Drug Description. Cisplatin. A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Nedaplatin. Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers . Oxaliplatin.

WebGeneric Name Ondansetron DrugBank Accession Number DB00904 Background. A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. how many nuclei do smooth muscle haveCisplatin DrugBank Accession Number DB00515 Background. Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and … See more how big is an a4WebGeneric Name Adalimumab DrugBank Accession Number DB00051 Background. Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. 2,3 It was originally launched by Abbvie in the U.S. and approved in 2002 by the … how big is an a4 page cmWebDaunorubicin is an anthracycline antibiotic and antineoplastic agent. 5 It acts by inhibiting cellular reproduction through interference with DNA replication although it may contribute to the induction of cell death by increasing oxidative stress through the generation of reactive oxygen species and free radicals. how many nucleotides make a geneWebDec 31, 2015 · Generic Name Levofloxacin DrugBank Accession Number DB01137 Background. Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. 1 It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin 1 and remains … how many nuclear weapons north korea haveWebDurvalumab (בתעתיק עברי: דורוואלומאב; שם מסחרי: Imfinzi) היא תרופה המאושרת על ידי ה-FDA, לטיפול בסרטן שפותחה על ידי חברת Medimmune\Astrazenica.זהו נוגדן מונוקלונאלי אנושי (Immunoglobulin G1 Kappa(IgG1k)), אשר חוסם את האינטראקציה בין החלבון החוץ תאי PD-1 ... how many nuclei in cardiac muscleWebDiscover expert tips and tricks on loading DrugBank SQL Files Read Guide. Durvalumab Recruiting Phase 2 Trials for Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC) / Adenocarcinoma of the Lung / Stage III Lung Cancer AJCC v8 / Lung Large Cell Carcinoma Treatment. Back to Durvalumab. Indications how many nucleotides in dna strand